APSP J Case Rep: Vol. 5 Issue 1: p. 12
Copyright © 2014 Wiwanitkit
Received Day: 05 Month: 01 Year: 2014
Accepted Day: 11 Month: 01 Year: 2014
APSP J Case Rep 2014; 5(1):12
Neonatal Cullen's Sign
Viroj Wiwanitkit Affiliation: Visiting Professor, Hainan Medical University, China; visiting professor, Faculty of Medicine, University of Nis, Serbia; adjunct professor, Joseph Ayobabalola University, Nigeria
Correspondence: Address for Correspondence:Professor Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok [email protected]

Dear Sir,

The recent report on Neonatal Cullen's Sign is very interesting [1]. Pederiva mentioned Neonatal Cullen's Sign as a distinguishing feature of intrauterine volvulus with hemorrhagic ascites.[1] Indeed, Cullen's Sign is a basic sign in medicine. It might imply the hemorrhage but it is not specific. Some non-hemorrhagic problems might also present Cullen's Sign. The good examples are the amebic infection [2] and cancer.[3] For intrauterine volvulus with hemorrhagic ascites, the diagnostic clue should be the ultrasonographic finding.[4,5]

Footnotes

Source of Support: Nil

Conflict of Interest: None declared

References
1. Pederiva F, De Cunto A, Paviotti G, Codrich D, Demarini S. Neonatal Cullen's sign: a distinguishing feature of intrauterine volvulus with hemorrhagic ascites. APSP J Case Rep. 2013; 4:53.
2. Misra A, Agrahari D, Gupta R. Cullen's sign in amoebic liver abscess. Postgrad Med J. 2002; 78:427-8.
3. Marinella MA, Baumann M. Cullen's sign associated with metastatic esophageal carcinoma. J Hosp Med. 2008; 3:277-8.
4. Witter FR, Molteni RA. Intrauterine intestinal volvulus with hemoperitoneum presenting as fetal distress at 34 weeks' gestation. Am J Obstet Gynecol. 1986; 155:1080-1.
5. Nijagal A, Rand L, Goldstein R, Poder L, Miniati D. Intrauterine umbilical cord hemorrhage with associated jejunal atresia captured by real-time ultrasound. Am J Obstet Gynecol. 2009; 200:e5-6.

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